September 2018: Biasiucci et al (2018) Brain-actuated functional electrical stimulation elicits lasting arm motor recovery after stroke. Nature Communications, 2421 https://www.nature.com/articles/s41467-018-04673-z
This is most definitely an article that all those with an interest in upper limb recovery should read. Not only is this because it has been published in “Nature” (a “dream” that every scientist has, but very, very few achieve!), it is also revolutionary! Yes, that’s right. Evidence like this will revolutionise future upper limb management!! This is not an easy article to read or understand, but it will be worth persisting.
At the start of their discussion, the authors claim that: “BCI–FES therapy resulted in a statistically significant, clinically important, and lasting reduction of impairment in chronic moderate-to-severe stroke patients. In particular, the preservation of clinically relevant improvements at least 6 months after end of therapy is remarkable”. This is “watershed” evidence that closes a loop, that to date, had not been closed. I often refer to stroke as a “brain-based problem that needs a brain-based solution”, and, for the first time, we have evidence that closing the feedback loop between the brain and the upper limb is worthwhile. A remarkable finding indeed!
This article is fully available and well worth reading in my humble opinion. Select the Journal Club 2018 page if you want to view the abstract. The rest of my humble opinion is added as a comment to this post.